THE USE OF ORAL LABETALOL IN THE TREATMENT OF ARRHYTHMIAS ASSOCIATED WITH THE LONG QT SYNDROME

被引：13

作者：

GRUBB, BP

机构：

[1] Medical College of Ohio, Toledo, OH 43560

来源：

CHEST | 1991年 / 100卷 / 06期

关键词：

D O I：

10.1378/chest.100.6.1724

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

A 7-year-old white boy with the long QT syndrome began to experience recurrent syncope associated with torsade de pointes ventricular tachycardia in spite of beta-blocker therapy. The patient was therefore given a combined alpha-and beta-blocking agent (labetalol) with complete suppression of the syncopal episodes. This suggests a role for combined alpha- and beta-blocking agents in the therapy of arrhythmias associated with the long QT syndrome.

引用

收藏

页码：1724 / 1725

页数：2

相关论文

共 9 条

[1] ALPHA-ADRENOCEPTOR STIMULATION AND BLOCKADE MODULATES CESIUM-INDUCED EARLY AFTERDEPOLARIZATIONS AND VENTRICULAR TACHYARRHYTHMIAS IN DOGS [J].

BENDAVID, J ;

ZIPES, DP .

CIRCULATION, 1990, 82 (01) :225-233

[2] HERITABLE Q-T PROLONGATION WITHOUT DEAFNESS [J].

GARZA, LA ;

VICK, RL ;

NORA, JJ ;

MCNAMARA, DG .

CIRCULATION, 1970, 41 (01) :39-&

[3] THE LONG QT SYNDROMES - A CRITICAL-REVIEW, NEW CLINICAL OBSERVATIONS AND A UNIFYING HYPOTHESIS [J].

JACKMAN, WM ;

FRIDAY, KJ ;

ANDERSON, JL ;

ALIOT, EM ;

CLARK, M ;

LAZZARA, R .

PROGRESS IN CARDIOVASCULAR DISEASES, 1988, 31 (02) :115-172

[4]

KASADA S, 1990, J CARDIOVASC ELECTRO, V1, P31

[5] THE LONG QT SYNDROME - A PROSPECTIVE INTERNATIONAL STUDY [J].

MOSS, AJ ;

SCHWARTZ, PJ ;

CRAMPTON, RS ;

LOCATI, E ;

CARLEEN, E .

CIRCULATION, 1985, 71 (01) :17-21

[6]

MOSS AJ, 1971, NEW ENGL J MED, V285, P902

[7] IDIOPATHIC LONG QT SYNDROME - PROGRESS AND QUESTIONS [J].

SCHWARTZ, PJ .

AMERICAN HEART JOURNAL, 1985, 109 (02) :399-411

[8] PHARMACODYNAMICS OF INTRAVENOUS LABETALOL AND FOLLOW-UP THERAPY WITH ORAL LABETALOL [J].

VLACHAKIS, ND ;

MARONDE, RF ;

MALOY, JW ;

MEDAKOVIC, M ;

KASSEM, N .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1985, 38 (05) :503-508

[9] FUNCTIONAL DISTRIBUTION OF RIGHT AND LEFT STELLATE INNERVATION TO VENTRICLES - PRODUCTION OF NEUROGENIC ELECTROCARDIOGRAPHIC CHANGES BY UNILATERAL ALTERATION OF SYMPATHETIC TONE [J].

YANOWITZ, F ;

PRESTON, JB ;

ABILDSKO.JA .

CIRCULATION RESEARCH, 1966, 18 (04) :416-&