IDENTIFICATION OF A 5-HT1A RECEPTOR POSITIVELY COUPLED TO PLANARIAN ADENYLATE-CYCLASE

被引：17

作者：

CRETI, P

CAPASSO, A

GRASSO, M

PARISI, E

机构：

[1] CNR,INST PROT BIOCHEM & ENZYMOL,NAPLES,ITALY

[2] UNIV LECCE,DEPT BIOL,I-73100 LECCE,ITALY

来源：

CELL BIOLOGY INTERNATIONAL REPORTS | 1992年 / 16卷 / 05期

关键词：

D O I：

10.1016/S0309-1651(06)80062-7

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The adenylate cyclase system present in particulate fractions prepared from two planarian species was tested for sensitivity to various neurotransmitters. While dopamine and other catecholamines were ineffective, serotonin was capable of stimulating the enzyme. Among the various serotonin agonists tested, only 8-OH-DPAT resulted effective on the adenylate cyclase activity, thus suggesting the presence in planarians of a serotonin receptor of the type 5-HT1A. © 1992 Academic Press Ltd.

引用

页码：427 / 432

页数：6

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