DETECTION OF BRAIN ACTIVATION USING OXYGENATION SENSITIVE FUNCTIONAL SPECTROSCOPY

被引：46

作者：

HENNIG, T ^{[1
]}

ERNST, T ^{[1
]}

SPECK, O ^{[1
]}

DEUSCHL, G ^{[1
]}

FEIFEL, E ^{[1
]}

机构：

[1] UNIV FREIBURG,NEUROL KLIN,FREIBURG,GERMANY

来源：

MAGNETIC RESONANCE IN MEDICINE | 1994年 / 31卷 / 01期

关键词：

FUNCTIONAL IMAGING; FUNCTIONAL SPECTROSCOPY; PHOTIC STIMULATION; MOTOR STIMULATION;

D O I：

10.1002/mrm.1910310115

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

A nonwater-suppressed localized spectroscopy experiment using the PRESS-sequence has been used to study the signal changes of the water resonance during cortical activation. Significant effects with an effect-to-noise ratio up to 50:1 for a single shot experiment have been observed upon photic stimulation. The exceedingly high signal-to-noise ratio of the experiment was used to demonstrate signal changes as low as 0.1% after electrical stimulation of the median nerve.

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页码：85 / 90

页数：6

相关论文

共 14 条

[1] TIME COURSE EPI OF HUMAN BRAIN-FUNCTION DURING TASK ACTIVATION [J].

BANDETTINI, PA ;

WONG, EC ;

HINKS, RS ;

TIKOFSKY, RS ;

HYDE, JS .

MAGNETIC RESONANCE IN MEDICINE, 1992, 25 (02) :390-397

[2] FUNCTIONAL CEREBRAL IMAGING BY SUSCEPTIBILITY-CONTRAST NMR [J].

BELLIVEAU, JW ;

ROSEN, BR ;

KANTOR, HL ;

RZEDZIAN, RR ;

KENNEDY, DN ;

MCKINSTRY, RC ;

VEVEA, JM ;

COHEN, MS ;

PYKETT, IL ;

BRADY, TJ .

MAGNETIC RESONANCE IN MEDICINE, 1990, 14 (03) :538-546

[3] FUNCTIONAL MAPPING OF THE HUMAN VISUAL-CORTEX BY MAGNETIC-RESONANCE-IMAGING [J].

BELLIVEAU, JW ;

KENNEDY, DN ;

MCKINSTRY, RC ;

BUCHBINDER, BR ;

WEISSKOFF, RM ;

COHEN, MS ;

VEVEA, JM ;

BRADY, TJ ;

ROSEN, BR .

SCIENCE, 1991, 254 (5032) :716-719

[4] FUNCTIONAL MRI OF HUMAN BRAIN ACTIVATION AT HIGH SPATIAL-RESOLUTION [J].

FRAHM, J ;

MERBOLDT, KD ;

HANICKE, W .

MAGNETIC RESONANCE IN MEDICINE, 1993, 29 (01) :139-144

[5]

FRAHM J, 1992, 11TH P SMRM M BERL, P306

[6]

HENNIG J, 1993, 12TH ANN M SOC MAGN, P12

[7]

HERRMANN M, IN PRESS J NEUROL NE

[8] DYNAMIC MAGNETIC-RESONANCE-IMAGING OF HUMAN BRAIN ACTIVITY DURING PRIMARY SENSORY STIMULATION [J].

KWONG, KK ;

BELLIVEAU, JW ;

CHESLER, DA ;

GOLDBERG, IE ;

WEISSKOFF, RM ;

PONCELET, BP ;

KENNEDY, DN ;

HOPPEL, BE ;

COHEN, MS ;

TURNER, R ;

CHENG, HM ;

BRADY, TJ ;

ROSEN, BR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (12) :5675-5679

[9]

OGAWA S, 1992, 11TH P ANN M SMRM BE, P303

[10] OXYGENATION DEPENDENCE OF THE TRANSVERSE RELAXATION-TIME OF WATER PROTONS IN WHOLE-BLOOD AT HIGH-FIELD [J].

THULBORN, KR ;

WATERTON, JC ;

MATTHEWS, PM ;

RADDA, GK .

BIOCHIMICA ET BIOPHYSICA ACTA, 1982, 714 (02) :265-270