HOMING OF NAIVE, MEMORY AND EFFECTOR LYMPHOCYTES

被引：267

作者：

MACKAY, CR

机构：

[1] The Basel Institute for Immunology, Basel

来源：

CURRENT OPINION IN IMMUNOLOGY | 1993年 / 5卷 / 03期

关键词：

D O I：

10.1016/0952-7915(93)90063-X

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Lymphocyte subsets home in a particular manner depending on their class, state of activation and 'allegiance' to certain tissues. Naive lymphocytes home preferentially through lymphoid tissues, whereas effector and memory cells home preferentially through non-lymphoid tissues and exist as phenotypically distinct subsets with preferential localization to gut, skin or other tissues. These migration pathways, which correlate with different functional properties of lymphocyte subsets, increase the efficiency of the immune system.

引用

页码：423 / 427

页数：5

共 30 条

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