COCAINE-INDUCED INTRACEREBRAL HEMORRHAGE - ANALYSIS OF PREDISPOSING FACTORS AND MECHANISMS CAUSING HEMORRHAGIC STROKES

被引：43

作者：

KIBAYASHI, K

MASTRI, AR

HIRSCH, CS

机构：

[1] OFF CHIEF MED EXAMINER,NEW YORK,NY 10016

[2] NYU,SCH MED,DEPT FORENS MED & PATHOL,NEW YORK,NY

来源：

HUMAN PATHOLOGY | 1995年 / 26卷 / 06期

关键词：

COCAINE; INTRACEREBRAL HEMORRHAGE; HYPERTENSIVE CARDIOVASCULAR DISEASE; CEREBRAL BLOOD FLOW; CEREBROVASCULAR AUTOREGULATION;

D O I：

10.1016/0046-8177(95)90172-8

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

We analyzed 26 autopsy cases of cocaine induced intracerebral hemorrhage and compared those findings with those of 26 autopsy cases of cocaine induced cerebral aneurysm rupture. The incidence of hypertensive cardiovascular disease (HCVD) was significantly higher in persons with intracerebral hemorrhage than in those with aneurysm rapture. Our findings suggest that HCVD predisposes to cocaine induced intracerebral hemorrhage. We propose that the foregoing relationship results from a cocaine induced alteration of cerebral autoregulation in the context of increased cerebral blood flow. Copyright (C) 1995 by W.B. Saunders Company

引用

页码：659 / 663

页数：5

共 23 条

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