DIHYDROPYRIDAZINONE CARDIOTONICS - THE DISCOVERY AND INOTROPIC ACTIVITY OF 1,3-DIHYDRO-3,3-DIMETHYL-5-(1,4,5,6-TETRAHYDRO-6-OXO-3-PYRIDAZINYL)-2H-INDOL-2-ONE

被引：85

作者：

ROBERTSON, DW

KRUSHINSKI, JH

BEEDLE, EE

WYSS, V

POLLOCK, GD

WILSON, H

KAUFFMAN, RF

HAYES, JS

机构：

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1986年 / 29卷 / 10期

关键词：

D O I：

10.1021/jm00160a006

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1832 / 1840

页数：9

共 56 条

[1] CHARACTERIZATION OF THE CARDIOTONIC EFFECTS OF MILRINONE, A NEW AND POTENT CARDIAC BIPYRIDINE, ON ISOLATED-TISSUES FROM SEVERAL ANIMAL SPECIES [J].

ALOUSI, AA ;

STANKUS, GP ;

STUART, JC ;

WALTON, LH .

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 1983, 5 (05) :804-811

[2]

ALOUSI AA, 1980, CIRC RES, V46, P887

[3]

BACHMANN G, 1967, Patent No. 1507475

[4] DOSE-RESPONSE FOLLOWING SINGLE ADMINISTRATIONS OF A NEW CARDIAC-PERFORMANCE ENHANCER RO-13-6438 IN NORMAL VOLUNTEERS [J].

BELZ, GG ;

STERN, HC ;

BUTZER, R .

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 1985, 7 (01) :86-90

[5] The catalytic reduction of nitrocinnamic acids and esters [J].

Blout, ER ;

Silverman, DC .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1944, 66 :1442-1443

[6]

BRISTOL JA, 1984, J MED CHEM, V27, P1101

[7] SYNTHESIS OF 7-PHENYLPYRIMIDO[5,4-D][1]BENZAZEPIN-2-ONES [J].

CHEN, WY ;

GILMAN, NW .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1983, 20 (03) :663-666

[8]

CHIEN CS, 1984, CHEM PHARM BULL, V32, P3945

[9]

COHN JN, 1983, DRUG TREATMENT HEART

[10] 6-PHENYL-4,5-DIHYDRO-3(H-2)-PYRIDAZINONES - SERIES OF HYPOTENSIVE AGENTS [J].

CURRAN, WV ;

ROSS, A .

JOURNAL OF MEDICINAL CHEMISTRY, 1974, 17 (03) :273-281

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