SYNTHESIS OF 3-BENZOYLCYCLOHEXANONE, A KEY INTERMEDIATE FOR THE SYNTHESIS OF KETOPROFEN

被引：2

作者：

BENNETAU, B

KREMPP, M

DUNOGUES, J

机构：

[1] Laboratoire de Chimie Organique et Organométallique, Université Bordeaux I, 351 Cours de la Libération, F-33405 Talence Cédex

来源：

SYNTHETIC COMMUNICATIONS | 1994年 / 24卷 / 01期

关键词：

D O I：

10.1080/00397919408012628

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple and convenient synthesis of 3-benzoylcyclohexanone, a ketoprofen precursor, is proposed. It consists of the preparation of 5-trimethylsilyl-3-cyclohexenone via disilylation of anisole followed by hydrolysis and subsequent regiospecific benzoylation and hydrogenation.

引用

页码：77 / 83

页数：7

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