NEW FLUORINE-CONTAINING BUILDING-BLOCKS FROM TRIFLUOROETHANOL .2.

被引：50

作者：

HOWARTH, JA

OWTON, WM

PERCY, JM

ROCK, MH

机构：

[1] UNIV BIRMINGHAM,SCH CHEM,BIRMINGHAM B15 2TT,W MIDLANDS,ENGLAND

[2] ELI LILLY & CO,LILLY RES CTR LTD,WINDLESHAM GU20 6PH,SURREY,ENGLAND

[3] FAC PHARM CHATENAY MALABRY,CNRS,BIOCIS,F-92296 CHATENAY MALABRY,FRANCE

来源：

TETRAHEDRON | 1995年 / 51卷 / 37期

关键词：

D O I：

10.1016/0040-4020(95)00588-Y

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new fluorine containing acyl anion equivalent 1,1 -difluoro-2-lithio-2-[(N,N-diethylcarbamato)-ethene 9 has been prepared and trapped with a number of electrophiles in good yields. Transacylation of the first formed lithium alkoxides releases a difluoroenolate, affording difluoromethylketones upon work-up.

引用

页码：10289 / 10302

页数：14

共 28 条

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