DETECTION OF ESTROGEN-RECEPTORS IN THE TRIGONUM AND URINARY-BLADDER WITH AN IMMUNOHISTOCHEMICAL TECHNIQUE

被引:8
作者
BUSSOLATI, G [1 ]
TIZZANI, A [1 ]
CASETTA, G [1 ]
CASSONI, P [1 ]
PACCHIONI, D [1 ]
PIANA, P [1 ]
REVELLI, A [1 ]
MASSOBRIO, M [1 ]
机构
[1] UNIV TURIN,OSP MAURIZIANO UMBERTO I,FAC CLIN OBSTET & GYNECOL D,REPARTO 5C,LARGO TURATI 62,I-10128 TURIN,ITALY
关键词
D O I
10.3109/09513599009009807
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In order to detect estrogen receptors (ER) in the female bladder, 5 pre-menopausal and 10 postmenopausal women affected by gynecological diseases were submitted to cystoscopy, during which both the trigonum and the bladder lateral wall were biopsied. A new, simple, cost-effective immunohistochemical technique was employed to stain the estrogen specific binding sites. ER were found in the trigonum of 3 premenopausal and 4 postmenopausal subjects, while the bladder lateral wall was always ER-negative. A comparison with previously used ER detection methods and a discussion of further hypothetical applications of the immunohistochemical technique in the study of the lower female urogenital tract are reported. © 1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
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页码:205 / 213
页数:9
相关论文
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