AVOIDING OXIDATIVE-DEGRADATION DURING SODIUM-HYDROXIDE METHYL IODIDE-MEDIATED CARBOHYDRATE METHYLATION IN DIMETHYL-SULFOXIDE

被引：499

作者：

NEEDS, PW

SELVENDRAN, RR

机构：

[1] Department of Food Molecular Biochemistry, AFRC Institute of Food Research, Norwich Laboratory, Norwich

来源：

CARBOHYDRATE RESEARCH | 1993年 / 245卷 / 01期

关键词：

D O I：

10.1016/0008-6215(93)80055-J

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A comparison of the methylation of cellobiitol by the Hakomori method (using potassium methylsulfinylmethanide - ''potassium dimsyl'' - as base) and by a published or a modified sodium hydroxide-mediated procedure is described. Evidence is presented that the modified sodium hydroxide-catalysed procedure is not prone to the oxidative deficiencies of the original and that, given its reduced tendency towards polysaccharide undermethylation, it should now become the method of choice for the methylation of these polymers.

引用

页码：1 / 10

页数：10

共 18 条

[1] A SIMPLE AND RAPID METHOD FOR THE PERMETHYLATION OF CARBOHYDRATES [J].