ORNITHINE-DELTA-AMINOTRANSFERASE IN LACTATING BOVINE MAMMARY-GLANDS

被引：10

作者：

BASCH, JJ ^{[1
]}

WICKHAM, ED ^{[1
]}

FARRELL, HM ^{[1
]}

KEYS, JE ^{[1
]}

机构：

[1] USDA ARS,BELTSVILLE AGR RES CTR,BELTSVILLE,MD 20705

来源：

JOURNAL OF DAIRY SCIENCE | 1995年 / 78卷 / 04期

关键词：

MILK SECRETION; ENZYMES; PROLINE;

D O I：

10.3168/jds.S0022-0302(95)76694-2

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

The occurrence and subcellular distribution of ornithine-delta-aminotransferase have been studied in lactating bovine mammary glands. The enzyme is localized in the mitochondria and has a unique thermal reaction profile that distinguishes it from putative liver and kidney isozymes. The enzyme concentration in the gland correlates well with a role in the conversion of ornithine into the proline precursor, L-Delta(1)-pyrroline-5-carboxylate. However, an unusually high Michaelis constant for the mitochondrial enzyme (8.4 mM) raises the question of enzyme efficiency in vivo such that this pathway needs to be considered in estimating barriers to protein secretion into milk.

引用

页码：825 / 831

页数：7

共 18 条

[1] DISTRIBUTION OF ADENOSINE-5'-DIPHOSPHATASE ACTIVITY IN THE LACTATING BOVINE MAMMARY-GLAND [J].