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NARCICLASINE-4-O-BETA-D-GLUCOPYRANOSIDE, A GLUCOSYLOXY AMIDIC PHENANTHRIDONE DERIVATIVE FROM PANCRATIUM-MARITIMUM

被引：32
作者：
ABOUDONIA, AH
DEGIULIO, A
EVIDENTE, A
GABER, M
HABIB, AA
LANZETTA, R
ELDIN, AAS
机构：
[1] CNR,IST CHIM MOLEC INTERESSE BIOL,I-80072 ARCO,ITALY
[2] UNIV NAPOLI FREDERICO 2,DIPARTIMENTO CHIM ORGAN & BIOL,I-80134 NAPLES,ITALY
[3] UNIV NAPOLI FREDERICO 2,DIPARTIMENTO SCI CHIM AGR,I-80055 PORTICI,ITALY
来源：
PHYTOCHEMISTRY | 1991年 / 30卷 / 10期
关键词：
PANCRATIUM-MARITIMUM; AMARYLLIDACEAE; BULBS; ALKALOIDS; NARCICLASINE; GLUCOSYLOXY ALKALOIDS; NARCICLASINE-4-O-BETA-D-GLUCOPYRANOSIDE;
D O I：
10.1016/0031-9422(91)83226-B
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Bulbs of Pancratium maritimum were found to contain a new glucosyloxy phenolic metabolite as well as 14 known Amaryllidaceae alkaloids. The structure of the phenolic metabolite was elucidated by spectroscopic and chemical methods, and it was identified as narciclasine-4-O-beta-D-glucopyranoside. When tested in Artemia salina and potato disc assays the new glucoside showed cytotoxic and antitumour activity very similar to narciclasine.
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页码：3445 / 3448
页数：4
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