BIOSYNTHESIS OF VITAMIN-B12 - THE SITE OF REDUCTION OF PRECORRIN-6X

被引：22

作者：

WEAVER, GW

LEEPER, FJ

BATTERSBY, AR

BLANCHE, F

THIBAUT, D

DEBUSSCHE, L

机构：

[1] UNIV CAMBRIDGE, CHEM LAB, LENSFIELD RD, CAMBRIDGE CB2 1EW, ENGLAND

[2] CTR RECH VITRY ALFORTVILLE, DEPT ANALYSE, F-94403 VITRY, FRANCE

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1991年 / 14期

关键词：

D O I：

10.1039/c39910000976

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

It is proved by deuterium labelling and NMR spectroscopy that a hydride equivalent from NADPH is transferred to C-19 of precorrin-6x as this intermediate is converted enzymically into hydrogenobyrinic acid.

引用

页码：976 / 979

页数：4

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