GOODPASTURES-LIKE SYNDROME AND EFFECT OF EXTRACORPOREAL MEMBRANE-OXYGENATOR SUPPORT

被引：12

作者：

DAIMON, S

UMEDA, T

MICHISHITA, I

WAKASUGI, H

GENDA, A

KONI, I

机构：

[1] Department of Internal Medicine, Kanazawa University School of Medicine, Kanazawa 920

来源：

INTERNAL MEDICINE | 1994年 / 33卷 / 09期

关键词：

RAPIDLY PROGRESSIVE GLOMERULONEPHRITIS; PULMONARY HEMORRHAGE;

D O I：

10.2169/internalmedicine.33.569

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 49-year-old man was admitted because of general fatigue, cough and hematuria. During the hospital course, acute renal failure, hemoptysis and dyspnea developed. A percutaneous renal biopsy revealed a diffuse crescentic glomerulonephritis, and direct immunofluorescence showed a linear pattern of IgG along the glomerular basement membrane. Although serum anti-glomerular basement membrane (anti-GBM) antibody was not detected, Goodpasture's-like syndrome was suspected, and methylprednisolone pulse therapy and plasmapheresis were administered. Concomitantly, extracorporeal membrane oxygenation (ECMO) was instituted because of deterioration in respiratory status due to a severe pulmonary hemorrhage despite maximal ventilatory support. Temporarily, the patient improved and ECMO was discontinued. ECMO may be a useful therapeutic support for hypoxia resulting from pulmonary hemorrhage in Goodpasture's syndrome (GPS) and Goodpasture's-like syndrome.

引用

页码：569 / 573

页数：5

共 16 条

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