PRESENCE OF GONADOTROPIN-RELEASING-HORMONE MESSENGER-RNA IN THE RAT OLFACTORY PIRIFORM CORTEX

被引：14

作者：

CHOI, WS

KIM, MO

LEE, BJ

KIM, JH

SUN, W

SEONG, JY

KIM, KJ

机构：

[1] UNIV ULSAN, COLL NAT SCI, DEPT BIOL, ULSAN 680749, SOUTH KOREA

[2] GYEONGSANG NATL UNIV, COLL MED, DEPT ANAT, CHINJU, SOUTH KOREA

[3] SEOUL NATL UNIV, COLL NAT SCI, DEPT MOLEC BIOL, SEOUL 151742, SOUTH KOREA

[4] SEOUL NATL UNIV, COLL NAT SCI, CELL DIFFERENTIAT RES CTR, SEOUL 151742, SOUTH KOREA

来源：

BRAIN RESEARCH | 1994年 / 648卷 / 01期

关键词：

GNRH MESSENGER-RNA; OLFACTORY PIRIFORM CORTEX; EXTRAHYPOTHALMUS;

D O I：

10.1016/0006-8993(94)91914-3

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Gonadotropin releasing hormone (GnRH) neurons are known to be originated from the olfactory placode and to enter the forebrain regions during embryonic development. The present study aims to ascertain whether GnRH is locally expressed in the olfactory cortex. Northern blot hybridization and reverse transcription-polymerase chain reaction revealed that GnRH mRNA was present in the rat olfactory cortex as well as in the olfactory bulb. The predicted size of GnRH mRNA is similar to that detected in the hypothalamus. In situ hybridization histochemistry also showed that GnRH mRNA is highly concentrated in the olfactory piriform cortex. The present data indicate that GnRH is synthesized in the olfactory piriform cortex.

引用

页码：148 / 151

页数：4

共 21 条

[1] ISOLATION OF THE GENE AND HYPOTHALAMIC CDNA FOR THE COMMON PRECURSOR OF GONADOTROPIN-RELEASING-HORMONE AND PROLACTIN RELEASE-INHIBITING FACTOR IN HUMAN AND RAT [J].