IMMUNOMODULATION IN HUMANS CAUSED BY BETA-CAROTENE AND VITAMIN-A

被引：31

作者：

PRABHALA, RH

GAREWAL, HS

MEYSKENS, FL

WATSON, RR

机构：

[1] UNIV ARIZONA,DEPT FAMILY & COMMUNITY MED,TUCSON,AZ 85724

[2] UNIV ARIZONA,DEPT MICROBIOL & IMMUNOL,TUCSON,AZ 85724

[3] UNIV ARIZONA,DEPT HEMATOL & ONCOL,TUCSON,AZ 85724

来源：

NUTRITION RESEARCH | 1990年 / 10卷 / 12期

关键词：

BETA CAROTENE; NATURAL KILLER CELLS; ACTIVATED LYMPHOCYTES; CANCER;

D O I：

10.1016/S0271-5317(05)80139-3

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Carotenoids and retinoids can stimulate some human immune responses. These include cytokine release with anti-tumor cell activity, increased natural killer cells and activated lymphocytes after both in vitro and in vivo treatment with beta carotene. Such stimulations seem only partly due to retinoids formed from carotenoid metabolism and may be due to effects caused by the structure of beta carotene. Changes in immune functions could explain in part the cancer resistance provided by high carotenoid or retinoid intakes in animals.

引用

页码：1473 / 1486

页数：14

共 58 条

[1]

ABB J, 1980, EXP CELL BIOL, V48, P169

[2] BETA-CAROTENE STIMULATES HUMAN-LEUKOCYTES TO SECRETE A NOVEL CYTOKINE [J].