THE RESPONSE OF SUPRACHIASMATIC NEURONS OF THE RAT HYPOTHALAMUS TO PHOTIC AND SEROTONERGIC STIMULATION

被引：60

作者：

MILLER, JD ^{[1
]}

FULLER, CA ^{[1
]}

机构：

[1] UNIV CALIF DAVIS,DEPT ANIM PHYSIOL,DAVIS,CA 95616

来源：

BRAIN RESEARCH | 1990年 / 515卷 / 1-2期

关键词：

Hypothalamus; Light; Metergoline; Quipazine; Serotonin;

D O I：

10.1016/0006-8993(90)90590-8

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Single-unit activity of the rat suprachiasmatic nucleus and surrounding regions was recorded in vivo. Photically responsive neurons were typically inhibited by low intravenous doses of the serotonin (5-HT) agonist quipazine. The 5-HT antagonist, metergoline, administered in a low intravenous dose, reversed the effects of quipazine. The subsequent response to photic stimulation was essentially identical to the initial photic response. Thus the photic response of neurons in the suprachiasmatic nucleus (SCN) and adjacent regions is relatively uninfluenced by 5-HT blockade. © 1990.

引用

页码：155 / 162

页数：8

共 45 条

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[2] CIRCADIAN CORTICOSTERONE RHYTHM DID NOT DEVELOP IN RATS 7 WEEKS AFTER DESTRUCTION WITH 5,7-DIHYDROXYTRYPTAMINE OF THE SEROTONINERGIC NERVE-TERMINALS IN THE SUPRACHIASMATIC NUCLEUS AT THE AGE OF 16 DAYS [J].