SECONDARY METABOLITES BY CHEMICAL-SCREENING .6. CLEAVAGE OF ELAIOPHYLIN AND TRANSFORMATION INTO A SPIROKETAL BUILDING BLOCK

被引：6

作者：

HAMMANN, P ^{[1
]}

KRETZSCHMAR, G ^{[1
]}

机构：

[1] HOECHST AG,POSTFACH 800320,W-6230 FRANKFURT,GERMANY

来源：

TETRAHEDRON | 1990年 / 46卷 / 16期

关键词：

D O I：

10.1016/S0040-4020(01)87760-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel methodology for the controlled basic cleavage of the macrodiolide antibiotic elaiophylin (la) to the seco-acid ester 2a and further transformation into the spiroketal building blocks 4 and 5 under Lewis acid catalysis has been developed. © 1990.

引用

页码：5609 / 5616

页数：8

共 11 条

[1] APPROACHES TO AVERMECTIN ASSEMBLY - SYNTHESIS OF THE SPIROKETAL SYSTEM [J].