AWARENESS OF HYPERTENSION INCREASES BLOOD-PRESSURE AND SYMPATHETIC RESPONSES TO COLD PRESSOR TEST

被引：71

作者：

ROSTRUP, M

KJELDSEN, SE

EIDE, IK

机构：

[1] The Department of Internal Medicine, Oslo University Medical School, Ullevaal Hospital, Oslo

来源：

AMERICAN JOURNAL OF HYPERTENSION | 1990年 / 3卷 / 12期

关键词：

EPINEPHRINE; AWARENESS OF HYPERTENSION; DOPAMINE; CATECHOLAMINES; HEART RATE; HYPERTENSION LABELING; NOREPINEPHRINE; SYMPATHETIC TONE;

D O I：

10.1093/ajh/3.12.912

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

The present study was aimed at examining the effects of awareness of hypertension on blood pressure and sympathetic responses to the cold pressor test. Nineteen-year-old men with similarly elevated mean blood pressure at a medical screening, but without knowledge of this, were randomized into two groups. The first group (n = 16) was sent a letter saying that their pressure was too high, and the second (n = 13) was sent a neutral letter. Information increased mean blood pressure both after 15 min sitting, by a average of 11.5 Hg (P < .01), and after 30 min supine rest, by an average of 4.5 mm Hg (P < .05). Changes in heart rate (8.4 +/- 2.4 v 1.9 +/- 1.7 beats/min) and plasma epinephrine (0.11 +/- 0.04 v 0.01 +/- 0.03 nmol/L during execution of a cold pressor test were significantly greater in the informed group (P < .05). Plasma dopamine was lower in the informed group (P < .05). Thus, psychological stress caused by the awareness of hypertension may increase blood pressure and sympathetic responses to a provocative maneuver. Ideally, studied on sympathetic function in essential hypertension should be undertaken on subjects unaware of their blood pressure status.

引用

页码：912 / 917

页数：6

共 21 条

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