ASSESSMENT OF MYOCARDIAL NECROSIS IMMEDIATELY AFTER INTRACORONARY THROMBOLYSIS BY INTRACORONARY INJECTION OF TECHNETIUM-99M PYROPHOSPHATE

被引:10
作者
SCHOFER, J
STRITZKE, P
MONTZ, R
MATHEY, DG
机构
[1] UNIV HAMBURG, DEPT CARDIOL, D-2000 HAMBURG 20, GERMANY
[2] UNIV HAMBURG, DEPT NUCL MED, D-2000 HAMBURG 20, GERMANY
关键词
D O I
10.1093/oxfordjournals.eurheartj.a061717
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
To assess myocardial necrosis immediately after intracoronary thrombolysis, 201Tl and 99mTc pyrophosphate (99mTc PYP) were injected simultaneously into the coronary artery in 25 patients with acute transmural myocardial infarction. In 17 of the 25 patients, the occluded coronary artery was reopened. Minutes after the intracoronary injection of 99mTc PYP into the reopened coronary artery a localized accumulation was seen within the area of the 201Tl defect in all patients. Control i.v. scintigraphy, which was performed in 8 of these 17 patients 1-6 days later, and in 2 patients 18 and 42 days after infarction, revealed a 99mTc PYP spot similar to that of the acute intracoronary 99mTc PYP scintigram in all 10 patients. In the 8 of the 25 patients, in whom intracoronary thrombolysis failed, no localized 99mTc PYP accumulation was seen after injection into the infarct vessel. In 5 of these patients, a control i.v. scintigram, performed 1-8 days later, resulted in a 99mTc PYP spot in the area of the 201Tl defect. In the presence of therapeutic or spontaneous reperfusion 99mTc PYP scintigraphy may provide a useful method of assessing myocardial necrosis during the early stage of an acute myocardial infarction.
引用
收藏
页码:617 / 621
页数:5
相关论文
共 5 条
[1]  
MADDAHI J, 1982, CIRCULATION, V66, P86
[2]   NON-SURGICAL CORONARY-ARTERY RECANALIZATION IN ACUTE TRANSMURAL MYOCARDIAL-INFARCTION [J].
MATHEY, DG ;
KUCK, KH ;
TILSNER, V ;
KREBBER, HJ ;
BLEIFELD, W .
CIRCULATION, 1981, 63 (03) :489-497
[3]  
PARKEY RW, 1981, J NUCL MED, V22, P133
[4]   USE OF DUAL INTRACORONARY SCINTIGRAPHY WITH TL-201 AND TECHNETIUM-99M PYROPHOSPHATE TO PREDICT IMPROVEMENT IN LEFT-VENTRICULAR WALL MOTION IMMEDIATELY AFTER INTRACORONARY THROMBOLYSIS IN ACUTE MYOCARDIAL-INFARCTION [J].
SCHOFER, J ;
MATHEY, DG ;
MONTZ, R ;
BLEIFELD, W ;
STRITZKE, P .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1983, 2 (04) :737-744
[5]   DUAL RADIONUCLIDE STUDY OF MYOCARDIAL-INFARCTION - RELATIONSHIPS BETWEEN MYOCARDIAL UPTAKE OF POTASSIUM-43, TC-99M STANNOUS PYROPHOSPHATE, REGIONAL MYOCARDIAL BLOOD-FLOW AND CREATINE-PHOSPHOKINASE DEPLETION [J].
ZARET, BL ;
DICOLA, VC ;
DONABEDIAN, RK ;
PURI, S ;
WOLFSON, S ;
FREEDMAN, GS ;
COHEN, LS .
CIRCULATION, 1976, 53 (03) :422-428