ISOLATION AND STRUCTURE OF CECROPINS, INDUCIBLE ANTIBACTERIAL PEPTIDES, FROM THE SILKWORM, BOMBYX-MORI

被引：84

作者：

MORISHIMA, I ^{[1
]}

SUGINAKA, S ^{[1
]}

UENO, T ^{[1
]}

HIRANO, H ^{[1
]}

机构：

[1] NATL INST AGROBIOL RESOURCES, DEPT MOLEC BIOL, TSUKUBA, IBARAKI 305, JAPAN

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY | 1990年 / 95卷 / 03期

关键词：

D O I：

10.1016/0305-0491(90)90019-P

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. 1. Cecropins, inducible antibacterial peptides, were purified by simple two step chromatography from immunized larval hemolymph of the silkworm, Bombyx mori. 2. 2. The cecropins were further separated into four major and two minor forms by reverse-phase HPLC. 3. 3. The four major cecropins were sequenced and divided into two types, A and B, whose structures were quite similar to cecropins A and B of Hyalophora cecropia. 4. 4. Three of them contained an unusual amino acid, δ-hydroxylysine. 5. 5. No remarkable difference in antibacterial activity against E. coli was detected among these cecropins. © 1990.

引用

页码：551 / 554

页数：4

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