PERIPHERAL BENZODIAZEPINES POTENTIATE THE EFFECT OF ADENOSINE IN RAT VAS-DEFERENS

被引：11

作者：

ESCUBEDO, E

CAMARASA, J

PALLAS, M

ADZET, T

机构：

[1] Laboratory of Pharmacology and Pharmacognosy, Faculty of Pharmacy, University of Barcelona, Barcelona

来源：

JOURNAL OF PHARMACY AND PHARMACOLOGY | 1991年 / 43卷 / 01期

关键词：

D O I：

10.1111/j.2042-7158.1991.tb05448.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Ro 5-4864, diazepam, clonazepam and PK 11195 inhibit the responses of rat vas deferens following electrical stimulation in the rank order Ro 5-4864 > PK 11195 = diazepam > clonazepam. The adenosine-inhibited electrically-induced response was potentiated by Ro 5-4864 or diazepam, but not by clonazepam or PK 11195. This potentiation is due to an inhibition of the adenosine uptake system.

引用

页码：49 / 50

页数：2

共 9 条

[1]

CAMARASA J, 1989, Medical Science Research, V17, P655

[2]

CAMARASA J, 1988, Medical Science Research, V16, P903

[3] POTENTIATION OF THE EFFECTS OF ADENOSINE ON ISOLATED CARDIAC AND SMOOTH-MUSCLE BY DIAZEPAM [J].