HYPERACUTE REJECTION IN HEART ALLOGRAFTS

被引：7

作者：

KEMNITZ, J ^{[1
]}

CREMER, J ^{[1
]}

RESTREPOSPECHT, I ^{[1
]}

HAVERICH, A ^{[1
]}

ZIEMER, G ^{[1
]}

HEUBLEIN, B ^{[1
]}

BORST, HG ^{[1
]}

UYSAL, A ^{[1
]}

GEORGII, A ^{[1
]}

机构：

[1] HANNOVER UNIV, SCH MED, DEPT CARDIOVASC SURG, HANNOVER, GERMANY

来源：

PATHOLOGY RESEARCH AND PRACTICE | 1991年 / 187卷 / 01期

关键词：

HYPERACUTE REJECTION; HEART ALLOGRAFTS; TRANSPLANTATION;

D O I：

10.1016/S0344-0338(11)81040-X

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Hyperacute rejection in orthotopic heart allografts is a rare event. In our material from a total collective of 524 heart-transplanted patients, we have observed two cases of hyperacute rejection, which are presented in this case report. Histopathologically, this entity is characterized above all by the following triad: pronounced edema, hemorrhages, and regressive changes up to necroses of myocytes. Besides the well-known risk factors, our report draws attention to two further factors possibly associated with an increased risk of hyperacute rejection: 1) repeated cardiac surgery prior to the transplantation, and 2) presence of identical viral genomes in recipient's and donor's heart.

引用

页码：23 / 29

页数：7

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