REACTIVE METABOLITES OF CARCINOGENIC POLYCYCLIC-HYDROCARBONS - SYNTHESIS AND TRAPPING REACTION OF 9-HYDROXYBENZO[ALPHA]PYRENE 4,5-OXIDE

被引：4

作者：

BOCHNITSCHEK, W

SEIDEL, A

KUNZ, H

OESCH, F

机构：

[1] UNIV MAINZ,INST TOXIKOL,OBERE ZAHLBACHER STR 67,D-6500 MAINZ,FED REP GER

[2] UNIV MAINZ,INST ORGAN CHEM,D-6500 MAINZ,FED REP GER

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1985年 / 24卷 / 08期

关键词：

D O I：

10.1002/anie.198506991

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：699 / 700

页数：2

共 12 条

[1] INVIVO FORMATION OF BENZO(A)PYRENE DIOL EPOXIDE-DEOXYADENOSINE ADDUCTS IN THE SKIN OF MICE SUSCEPTIBLE TO BENZO(A)PYRENE-INDUCED CARCINOGENESIS [J].

ASHURST, SW ;

COHEN, GM .

INTERNATIONAL JOURNAL OF CANCER, 1981, 27 (03) :357-364

[2]

BOCHNETSCHEK W, UNPUB

[3]

GLATT HR, 1981, CANCER RES, V41, P270

[4] K-REGION OXIDIZED METABOLITES OF 9-HYDROXYBENZO[A]PYRENE [J].

HARVEY, RG ;

CORTEZ, C .

CARCINOGENESIS, 1983, 4 (07) :941-942

[5] ACTIVATED METABOLITES OF CARCINOGENIC HYDROCARBONS [J].

HARVEY, RG .

ACCOUNTS OF CHEMICAL RESEARCH, 1981, 14 (07) :218-226

[6] CHEMICAL REARRANGEMENT OF PHENOL-EPOXIDE METABOLITES OF POLYCYCLIC AROMATIC-HYDROCARBONS TO QUINONE-METHIDES [J].

HULBERT, PB ;

GROVER, PL .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1983, 117 (01) :129-134

[7] BENZO[A]PYRENE 7,8-DIHYDRODIOL IS MORE CARCINOGENIC THAN BENZO[A]PYRENE IN NEWBORN MICE [J].

KAPITULNIK, J ;

LEVIN, W ;

CONNEY, AH ;

YAGI, H ;

JERINA, DM .

NATURE, 1977, 266 (5600) :378-380

[8]

NEMETO N, 1975, NATURE LONDON, V255, P512

[9] EFFECTS OF THE MODULATION OF EPOXIDE HYDROLASE ACTIVITY ON THE BINDING OF BENZO[A]PYRENE METABOLITES TO DNA IN THE INTACT NUCLEI [J].

OESCH, F ;

GUENTHNER, TM .

CARCINOGENESIS, 1983, 4 (01) :57-65

[10]

PREUSSMA.R, 1969, ARZNEI-FORSCHUNG, V19, P1059

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