THE SYNTHESIS OF ISOXAZOLES FROM BETA,GAMMA-ACETYLENIC OXIMES

被引：30

作者：

SHORT, KM ^{[1
]}

ZIEGLER, CB ^{[1
]}

机构：

[1] AMER CYANAMID CO,LEDERLE LABS,DIV MED RES,PEARL RIVER,NY 10965

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 01期

关键词：

D O I：

10.1016/S0040-4039(00)60061-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Beta,gamma-acetylenic oximes (prepared from alpha-bromooximes) undergo facile conversion to 3,5-disubstituted isoxazoles on mild base treatment.

引用

页码：75 / 78

页数：4

共 11 条

[1] QUATERNARY PILOCARPINE DERIVATIVES AS POTENTIAL ACETYLCHOLINE ANTAGONISTS .2. ALTERATIONS IN LACTONE AND IMIDAZOLE MOIETIES [J].

BENBASSAT, AA ;

LAVIE, D ;

EDERY, H ;

PORATH, G .

JOURNAL OF MEDICINAL CHEMISTRY, 1976, 19 (07) :928-933

[2]

CORY EJ, 1977, HELV CHIM ACTA, V60, P2294

[3]

COUSSE H, 1986, ARZNEIMITTEL-FORSCH, V36-2, P1391

[4]

Grunanger P., 1991, CHEM HETEROCYCLIC 1, V49

[5] SMALL RINGS .25. SYNTHESIS OF SOME 1-AZIRINES FROM ALPHA-BROMO KETOXIMES VIA OXAZAPHOSPHOLINES [J].

HASSNER, A ;

ALEXANIAN, V .

JOURNAL OF ORGANIC CHEMISTRY, 1979, 44 (22) :3861-3864

[6] REACTION OF N-ALKYLISOXAZOLIUM SALTS WITH HYDROXYLAMINE [J].

KASHIMA, C ;

ARAI, K ;

IMADA, S ;

TSUDA, Y .

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1978, 51 (06) :1844-1845

[7]

MAFFRAND JP, 1975, EUR J MED CHEM, V10, P528

[8] BASE-CATALYZED CYCLIZATION OF N-PROPARGYLAMIDES TO OXAZOLES [J].

NILSSON, BM ;

HACKSELL, U .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1989, 26 (02) :269-275

[9]

NISHIOKA T, Patent No. 53092736

[10]

SHORT KT, COMMUNICATION

← 1 2 →