APPLICATION OF SOLID-PHASE EXTRACTION TO THE ISOLATION AND DETERMINATION OF PARACETAMOL AND ITS METABOLITES

被引：6

作者：

ELMOUELHI, M

BUSZEWSKI, B

机构：

[1] UNIV TUBINGEN,INST TOXICOL,W-7400 TUBINGEN 1,GERMANY

[2] UNIV TUBINGEN,INST ORGAN CHEM,W-7400 TUBINGEN 1,GERMANY

来源：

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 1990年 / 8卷 / 8-12期

关键词：

SOLID-PHASE EXTRACTION; CHEMICALLY BONDED PHASE; ACETAMINOPHENOLES; GLUCURONIDE AND GLUTATHIONE-DERIVED CONJUGATES;

D O I：

10.1016/0731-7085(90)80096-8

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A series of clean-up columns for solid-phase extraction (SPE) were packed with various C18 phases of different physico-chemical surface properties. These SPE columns were used for the isolation and determination of paracetamol and its metabolites from biological samples. The packing with a monomeric structure of chemically bonded phase showed the best recovery of tested substances in urine.

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收藏

页码：651 / 653

页数：3

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