SUBSTRATE-SPECIFICITY OF SOLUBLE RECOMBINANT DEACETOXYCEPHALOSPORIN C/DEACETYLCEPHALOSPORIN C SYNTHASE

被引：3

作者：

BALDWIN, JE ^{[1
]}

ADLINGTON, RM ^{[1
]}

CROUCH, NP ^{[1
]}

HEATH, RJ ^{[1
]}

PEREIRA, IAC ^{[1
]}

SUTHERLAND, JD ^{[1
]}

机构：

[1] OXFORD CTR MOLEC SCI,OXFORD OX1 3QY,ENGLAND

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1992年 / 2卷 / 07期

关键词：

D O I：

10.1016/S0960-894X(00)80387-X

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The substrate specificity of a new soluble recombinant deacetoxycephalosporin C/deacetylcephalosporin C synthase has been investigated and was found to be identical to that of the wild type fungal enzyme. Using the soluble enzyme, a new metabolite has been detected on incubation with [4-H-2]-exomethylene cephalosporin C.

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收藏

页码：669 / 672

页数：4

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