MAPPING OF THE FUNCTIONAL ACTIVE-SITE OF BAEYER-VILLIGERASES BY SUBSTRATE ENGINEERING

被引：40

作者：

KELLY, DR ^{[1
]}

KNOWLES, CJ ^{[1
]}

MAHDI, JG ^{[1
]}

TAYLOR, IN ^{[1
]}

WRIGHT, MA ^{[1
]}

机构：

[1] UNIV KENT, BIOL LAB, CANTERBURY CT2 7NJ, KENT, ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1995年 / 07期

关键词：

D O I：

10.1039/c39950000729

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An active sits model for enzyme catalysed Baeyer-Villiger reactions is proposed and validated by transformation of the tricyclic ketone 6; Baeyer-Villiger reactions (and Baeyer-Villigerases) are classified by the stereochemistry of the hydroxyperoxide intermediate.

引用

页码：729 / 730

页数：2

共 13 条

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