HIRUDIN AND OTHER THROMBIN INHIBITORS - EXPERIMENTAL RESULTS AND POTENTIAL CLINICAL-APPLICATIONS

被引：24

作者：

BADIMON, L

MERINO, A

BADIMON, J

CHESEBRO, JH

FUSTER, V

机构：

[1] MT SINAI HOSP, DIV CARDIOL, NEW YORK, NY 10029 USA

[2] MAYO CLIN, DIV CARDIOVASC DIS, ROCHESTER, MN 55901 USA

来源：

TRENDS IN CARDIOVASCULAR MEDICINE | 1991年 / 1卷 / 06期

关键词：

D O I：

10.1016/1050-1738(91)90032-A

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Thrombosis results from the activation of the hemostatic system by pathologic stimuli. It is a dynamic process that involves various blood cells and proteins, the nature of blood flow, and substrate characteristics. The classic description of the hemostatic system encompasses the coagulation and fibrinolytic systems, the platelets, and the endothelium. Thrombin plays a central role in thrombus formation, interacting with the components of the hemostatic system and vessel wall.

引用

页码：261 / 267

页数：7

共 36 条

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