ANTIMICROBIAL ACTIVITIES OF BETA-LACTAM ANTIBIOTICS AND GENTAMICIN AGAINST PENICILLIN-SUSCEPTIBLE AND PENICILLIN-RESISTANT PNEUMOCOCCI

被引：20

作者：

GROSS, ME

GIRON, KP

SEPTIMUS, JD

MASON, EO

MUSHER, DM

机构：

[1] DEPT VET AFFAIRS MED CTR,INFECT DIS SECT,MED SERV,HOUSTON,TX 77030

[2] BAYLOR COLL MED,DEPT MED,HOUSTON,TX 77030

[3] BAYLOR COLL MED,DEPT PEDIAT,HOUSTON,TX 77030

[4] BAYLOR COLL MED,DEPT MICROBIOL IMMUNOL,HOUSTON,TX 77030

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1995年 / 39卷 / 05期

关键词：

D O I：

10.1128/AAC.39.5.1166

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The MICs of penicillin and cefotaxime for a range of penicillin-susceptible and penicillin-resistant isolates of Streptococcus pneumoniae were unchanged by the addition of gentamicin. In time-kill studies the rate of killing was greater for 18 of 20 isolates in the presence of gentamicin. However, mean differences in killing after 6 h of incubation were modest, not exceeding 1 log(10) unit.

引用

收藏

页码：1166 / 1168

页数：3

相关论文

共 10 条

[1] INVIVO ANTIBIOTIC SYNERGISM - CONTRIBUTION OF ANIMAL-MODELS [J].

FANTIN, B ;

CARBON, C .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1992, 36 (05) :907-912

[2] DILEMMAS IN DIAGNOSIS AND MANAGEMENT OF CEPHALOSPORIN-RESISTANT STREPTOCOCCUS-PNEUMONIAE MENINGITIS [J].

FRIEDLAND, IR ;

SHELTON, S ;

PARIS, M ;

RINDERKNECHT, S ;

EHRETT, S ;

KRISHER, K ;

MCCRACKEN, GH .

PEDIATRIC INFECTIOUS DISEASE JOURNAL, 1993, 12 (03) :196-200

[3]

FRIMODTMOLLER N, 1987, ACTA PATH MICRO IM B, V95, P269

[4] THE INVITRO ACTIVITY OF COMBINATIONS OF PENICILLIN AND GENTAMICIN AGAINST PENICILLIN-RESISTANT AND PENICILLIN-SENSITIVE STREPTOCOCCUS-PNEUMONIAE [J].

HAYNES, J ;

HAWKEY, PM ;

WILLIAMS, EW .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1986, 18 (03) :426-428

[5] PHARMACOLOGIC EVALUATION OF PENICILLIN IN CHILDREN WITH PURULENT-MENINGITIS [J].

HIEBER, JP ;

NELSON, JD .

NEW ENGLAND JOURNAL OF MEDICINE, 1977, 297 (08) :410-413

[6] MULTICENTER EVALUATION OF THE USE OF HAEMOPHILUS TEST MEDIUM FOR BROTH MICRODILUTION ANTIMICROBIAL SUSCEPTIBILITY TESTING OF STREPTOCOCCUS-PNEUMONIAE AND DEVELOPMENT OF QUALITY-CONTROL LIMITS [J].

JORGENSEN, JH ;

DOERN, GV ;

FERRARO, MJ ;

KNAPP, CC ;

SWENSON, JM ;

WASHINGTON, JA .

JOURNAL OF CLINICAL MICROBIOLOGY, 1992, 30 (04) :961-966

[7] AMINOGLYCOSIDE THERAPY OF GRAM-NEGATIVE BACILLARY MENINGITIS [J].

KAISER, AB ;

MCGEE, ZA .

NEW ENGLAND JOURNAL OF MEDICINE, 1975, 293 (24) :1215-1220

[8] TESTING OF STREPTOCOCCUS-PNEUMONIAE FOR RESISTANCE TO PENICILLIN [J].

MARSHALL, KJ ;

MUSHER, DM ;

WATSON, D ;

MASON, EO .

JOURNAL OF CLINICAL MICROBIOLOGY, 1993, 31 (05) :1246-1250

[9] CHARACTERISTICS AND ANTIBIOTIC-THERAPY OF ADULT MENINGITIS DUE TO PENICILLIN-RESISTANT PNEUMOCOCCI [J].

VILADRICH, PF ;

GUDIOL, F ;

LINARES, J ;

RUFI, G ;

ARIZA, J ;

PALLARES, R .

AMERICAN JOURNAL OF MEDICINE, 1988, 84 (05) :839-846

[10]

[No title captured]