UTILIZATION OF A SELF-ASSEMBLED PEPTIDE MONOLAYER FOR AN IMPEDIMETRIC IMMUNOSENSOR

被引：68

作者：

KNICHEL, M

HEIDUSCHKA, P

BECK, W

JUNG, G

GOPEL, W

机构：

[1] UNIV TUBINGEN,INST PHYS & THEORET CHEM,D-72076 TUBINGEN,GERMANY

[2] UNIV TUBINGEN,INST ORGAN CHEM,D-72076 TUBINGEN,GERMANY

来源：

SENSORS AND ACTUATORS B-CHEMICAL | 1995年 / 28卷 / 02期

关键词：

IMPEDIMETRIC IMMUNOSENSORS; SELF-ASSEMBLED PEPTIDE MONOLAYERS;

D O I：

10.1016/0925-4005(94)01543-Q

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Layers of a thiol-containing synthetic peptide constituting an epitope of the foot-and-mouth-disease virus are formed on gold electrodes via self-assembly. The immunological reactivity of the modified electrodes towards a monoclonal antibody is confirmed by performing an ELISA. The binding of a specific antibody to epitope-modified gold electrodes can be detected by measuring changes of the Faradaic impedance.

引用

页码：85 / 94

页数：10

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