LACK OF EFFECT OF AN INSPIRATORY THRESHOLD LOAD ON PLASMA ATRIAL-NATRIURETIC-PEPTIDE LEVELS

被引：8

作者：

WARLEY, ARH

FONTES, F

WILSON, M

RAINE, AEG

STRADLING, JR

机构：

[1] CHURCHILL HOSP, OSLER CHEST UNIT, OXFORD OX3 7LJ, ENGLAND

[2] JOHN RADCLIFFE HOSP, NUFFIELD DEPT MED, OXFORD OX3 9DU, ENGLAND

来源：

CLINICAL SCIENCE | 1990年 / 78卷 / 03期

关键词：

Atrial natriuretic peptide; Inspiratory load; Urinary sodium; Urinary volume;

D O I：

10.1042/cs0780311

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

1. After a run-in period, six healthy, recumbent, waterloaded male subjects breathed through an inspiratory threshold load for 90 min. To correct for prolonged recumbency, a similar protocol was followed on a separate control day, but without an inspiratory load. 2. A negative intrathoracic pressure of at least 30 cmH2O was required to overcome the threshold load. 3. Urine was collected every 30 min and analysed for sodium concentration. 4. Plasma samples were collected every 30 min and analysed for atrial natriuretic peptide concentration. 5. The inspiratory load had no effect on urine volume, urinary sodium excretion or plasma atrial natriuretic peptide levels.

引用

页码：311 / 313

页数：3

共 16 条

[1] ATRIAL NATRIURETIC PEPTIDE - PHYSIOLOGICAL RELEASE ASSOCIATED WITH NATRIURESIS DURING NEGATIVE-PRESSURE BREATHING IN MAN [J].