THE PHORBOL ESTER TPA PREVENTS THE EXPRESSION OF BOTH GLUCAGON DESENSITIZATION AND THE GLUCAGON-MEDIATED BLOCK OF INSULIN STIMULATION OF THE PERIPHERAL PLASMA-MEMBRANE CYCLIC-AMP PHOSPHODIESTERASE IN RAT HEPATOCYTES

被引：28

作者：

HEYWORTH, CM

WILSON, SP

GAWLER, DJ

HOUSLAY, MD

机构：

[1] UNIV GLASGOW,INST BIOCHEM,GLASGOW G12 8QQ,SCOTLAND

[2] UNIV MANCHESTER,INST SCI & TECHNOL,DEPT BIOCHEM & APPL MOLEC BIOL,MANCHESTER M60 1QD,LANCS,ENGLAND

来源：

FEBS LETTERS | 1985年 / 187卷 / 02期

关键词：

D O I：

10.1016/0014-5793(85)81241-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：196 / 200

页数：5

共 21 条

[1] G-PROTEINS AND DUAL CONTROL OF ADENYLATE-CYCLASE [J].

GILMAN, AG .

CELL, 1984, 36 (03) :577-579

[2] CHALLENGE OF HEPATOCYTES BY GLUCAGON TRIGGERS A RAPID MODULATION OF ADENYLATE-CYCLASE ACTIVITY IN ISOLATED MEMBRANES [J].

HEYWORTH, CM ;

HOUSLAY, MD .

BIOCHEMICAL JOURNAL, 1983, 214 (01) :93-98

[3] INSULIN INHIBITS THE CHOLERA-TOXIN-CATALYZED RIBOSYLATION OF A MR-25000 PROTEIN IN RAT-LIVER PLASMA-MEMBRANES [J].

HEYWORTH, CM ;

WHETTON, AD ;

WONG, S ;

MARTIN, BR ;

HOUSLAY, MD .

BIOCHEMICAL JOURNAL, 1985, 228 (03) :593-603

[4] INSULIN EXERTS ACTIONS THROUGH A DISTINCT SPECIES OF GUANINE-NUCLEOTIDE REGULATORY PROTEIN - INHIBITION OF ADENYLATE-CYCLASE [J].

HEYWORTH, CM ;

HOUSLAY, MD .

BIOCHEMICAL JOURNAL, 1983, 214 (02) :547-552

[5] THE PHORBOL ESTER, TPA INHIBITS GLUCAGON-STIMULATED ADENYLATE-CYCLASE ACTIVITY [J].

HEYWORTH, CM ;

WHETTON, AD ;

KINSELLA, AR ;

HOUSLAY, MD .

FEBS LETTERS, 1984, 170 (01) :38-42

[6] INSULIN AND GLUCAGON REGULATE THE ACTIVATION OF 2 DISTINCT MEMBRANE-BOUND CYCLIC-AMP PHOSPHODIESTERASES IN HEPATOCYTES [J].

HEYWORTH, CM ;

WALLACE, AV ;

HOUSLAY, MD .

BIOCHEMICAL JOURNAL, 1983, 214 (01) :99-110

[7]

HEYWORTH CM, 1984, BIOCH J, V22, P189

[8] INSULIN - IN SEARCH OF A MECHANISM [J].

HOUSLAY, MD ;

HEYWORTH, CM .

TRENDS IN BIOCHEMICAL SCIENCES, 1983, 8 (12) :449-452

[9] CHOLERA TOXIN MEDIATED ACTIVATION OF ADENYLATE-CYCLASE IN INTACT RAT HEPATOCYTES [J].

HOUSLAY, MD ;

ELLIOTT, KRF .

FEBS LETTERS, 1979, 104 (02) :359-363

[10] PHORBOL ESTERS STIMULATE THE PHOSPHORYLATION OF RECEPTORS FOR INSULIN AND SOMATOMEDIN-C [J].

JACOBS, S ;

SAHYOUN, NE ;

SALTIEL, AR ;

CUATRECASAS, P .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (20) :6211-6213

← 1 2 3 →