RESPIRATORY SUPPRESSION BY FOCAL COOLING OF VENTRAL MEDULLARY SURFACE IN ANESTHETIZED RATS - FUNCTIONAL AND NEUROANATOMICAL CORRELATE

被引：14

作者：

FUKUDA, Y

TOJIMA, H

TANAKA, K

CHIBA, T

机构：

[1] CHIBA UNIV,SCH MED,DEPT CHEST MED,CHIBA 260,JAPAN

[2] CHIBA UNIV,SCH MED,DEPT ANAT,CHIBA 260,JAPAN

来源：

NEUROSCIENCE LETTERS | 1993年 / 153卷 / 02期

关键词：

VENTRAL MEDULLARY SURFACE; RESPIRATORY PATTERN; FOCAL COOLING; NEURON DISTRIBUTION; RAT;

D O I：

10.1016/0304-3940(93)90316-D

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Bilateral cooling of the parapyramidal region in the rostral ventral medullary surface (VMS) elicited a reduction in respiratory frequency and phrenic inspiratory activity in halothane anesthetized rats. A distinct cluster of neurons (nucleus parapyramidalis superficialis) was found in a superficial layer (10-150 mum from the surface)just beneath the area where cooling produced suppression of respiration. The rat VMS layer contains neural substrates which regulate the respiratory rhythm generation and inspiratory neural output.

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页码：177 / 180

页数：4

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