USE OF SENSITIVE TSH ASSAY TO DETERMINE OPTIMAL THYROID-HORMONE THERAPY AND AVOID OSTEOPOROSIS

被引：23

作者：

WARTOFSKY, L ^{[1
]}

机构：

[1] UNIFORMED SERV UNIV HLTH SCI,BETHESDA,MD 20814

来源：

ANNUAL REVIEW OF MEDICINE | 1991年 / 42卷

关键词：

THYROTROPIN; HYPERTHYROIDISM; BONE MINERAL;

D O I：

10.1146/annurev.med.42.1.341

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Reported deleterious effects of thyroid hormone on bone mineral density have alarmed clinicians and patients alike because of the potential risks of osteoporosis and fracture. The known adverse effects of excessive thyroid hormones on bone are briefly reviewed, with distinction made between the status and potential consequences of replacement versus suppressive therapy. Employing the newer ultrasensitive TSH assay, management guidelines are offered to the clinician that should minimize risks of osteopenia in patients taking thyroid hormone.

引用

页码：341 / 345

页数：5

共 16 条

[1] AHMANN AJ, 1990, PRINCIPLES PRACTICE, P312
[2] AHMANN AJ, 1987, 62ND M AM THYR ASS, pT21
[3] COINDRE JM, 1986, ARCH INTERN MED, V146, P48, DOI 10.1001/archinte.146.1.48
[4] ETTINGER B, 1982, WESTERN J MED, V136, P473
[5] EXOGENOUS HYPERTHYROIDISM WITH OSTEOPOROSIS
FALLON, MD
PERRY, HM
BERGFELD, M
DROKE, D
TEITELBAUM, SL
AVIOLI, LV
[J]. ARCHIVES OF INTERNAL MEDICINE, 1983, 143 (03) : 442 - 444
[6] SUPPRESSIVE THERAPY WITH LEVOTHYROXINE FOR SOLITARY THYROID-NODULES - A DOUBLE-BLIND CONTROLLED CLINICAL-STUDY
GHARIB, H
JAMES, EM
CHARBONEAU, JW
NAESSENS, JM
OFFORD, KP
GORMAN, CA
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1987, 317 (02) : 70 - 75
[7] L-THYROXINE DOSAGE - A REEVALUATION OF THERAPY WITH CONTEMPORARY PREPARATIONS
HENNESSEY, JV
EVAUL, JE
TSENG, YC
BURMAN, KD
WARTOFSKY, L
[J]. ANNALS OF INTERNAL MEDICINE, 1986, 105 (01) : 11 - 15
[8] ASSESSMENT OF SENSITIVE THYROTROPIN ASSAYS FOR AN EXPANDED ROLE IN THYROID-FUNCTION TESTING - PROPOSED CRITERIA FOR ANALYTIC PERFORMANCE AND CLINICAL UTILITY
KLEE, GG
HAY, ID
[J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1987, 64 (03) : 461 - 471
[9] EFFECTS OF THYROID-HORMONES ON BONE AND MINERAL METABOLISM
MOSEKILDE, L
ERIKSEN, EF
CHARLES, P
[J]. ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA, 1990, 19 (01) : 35 - 63
[10] LONG-TERM L-THYROXINE THERAPY IS ASSOCIATED WITH DECREASED HIP BONE-DENSITY IN PREMENOPAUSAL WOMEN
PAUL, TL
KERRIGAN, J
KELLY, AM
BRAVERMAN, LE
BARAN, DT
[J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1988, 259 (21): : 3137 - 3141

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