MONOCLONAL-ANTIBODY G1O WHICH RECOGNIZES MICROTUBULE-ASSOCIATED PROTEIN 1X IDENTIFIES GROWING AXONS OF NEURONS MICROTRANSPLANTED INTO ADULT-RAT HIPPOCAMPUS

被引：6

作者：

BROOK, GA

WOODHAMS, PL

SHAH, B

RAISMAN, G

机构：

[1] The Norman and Sadie Lee Research Centre, Laboratory of Neurobiology, National Institute for Medical Research. The Ridgeway, London, NW7 1AA, Mill Hill

来源：

NEUROSCIENCE LETTERS | 1993年 / 163卷 / 02期

关键词：

G10; MICROTUBULE-ASSOCIATED PROTEIN; TRANSPLANTATION; AXON; DEVELOPMENT;

D O I：

10.1016/0304-3940(93)90368-U

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Monoclonal antibody G10 recognises an epitope on microtubule-associated protein lx, a developmentally regulated cytoskeletal protein expressed in immature axons of the central and peripheral nervous systems. Here we report that G10 can be used to identify the axonal projections of syngeneic embryonic (E14-E15) hippocampal cells microtransplanted by a minimally traumatic technique into intact adult host hippocampus.

引用

页码：148 / 150

页数：3

共 10 条

[1] A MICROTUBULE-ASSOCIATED PROTEIN (MAP1) WHICH IS EXPRESSED AT ELEVATED LEVELS DURING DEVELOPMENT OF THE RAT CEREBELLUM
CALVERT, R
ANDERTON, BH
[J]. EMBO JOURNAL, 1985, 4 (05) : 1171 - 1176
[2] LOCALIZATION OF AN EPITOPE OF A MICROTUBULE-ASSOCIATED PROTEIN-1X IN OUTGROWING AXONS OF THE DEVELOPING RAT CENTRAL-NERVOUS-SYSTEM
CALVERT, RA
WOODHAMS, PL
ANDERTON, BH
[J]. NEUROSCIENCE, 1987, 23 (01) : 131 - 141
[3] MICROTRANSPLANTATION OF NEURAL CELLS INTO ADULT-RAT BRAIN
EMMETT, CJ
JAQUESBERG, W
SEELEY, PJ
[J]. NEUROSCIENCE, 1990, 38 (01) : 213 - 222
[4] MICROTUBULE-ASSOCIATED PROTEINS MAP5 AND MAP1X - CLOSELY RELATED COMPONENTS OF THE NEURONAL CYTOSKELETON WITH DIFFERENT CYTOPLASMIC DISTRIBUTIONS IN THE DEVELOPING BRAIN
GARNER, CC
MATUS, A
ANDERTON, B
CALVERT, R
[J]. MOLECULAR BRAIN RESEARCH, 1989, 5 (01): : 85 - 92
[5] KAPLAN MS, 1983, EXP BRAIN RES, V52, P1
[6] OLEARY DDM, 1990, COLD SPRING HARB SYM, V55, P453
[7] REIDERER BM, 1993, NEUROREPORT, V4, P771
[8] MONOCLONAL-ANTIBODY G10 AGAINST MICROTUBULE-ASSOCIATED PROTEIN 1X DISTINGUISHES BETWEEN GROWING AND REGENERATING AXONS
WOODHAMS, PL
CALVERT, R
DUNNETT, SB
[J]. NEUROSCIENCE, 1989, 28 (01) : 49 - 59
[9] WOODHAMS PL, 1989, J NEUROSCI, V9, P2170
[10] WOODHAMS PL, IN PRESS EUR J NEURO

← 1 →