PATELLAMIDE-F, A NEW CYTOTOXIC CYCLIC PEPTIDE FROM THE COLONIAL ASCIDIAN LISSOCLINUM-PATELLA

被引：47

作者：

RASHID, MA ^{[1
]}

GUSTAFSON, KR ^{[1
]}

CARDELLINA, JH ^{[1
]}

BOYD, MR ^{[1
]}

机构：

[1] NCI,DIV CANC TREATMENT,DEV THERAPEUT PROGRAM,DRUG DISCOVERY RES & DEV LAB,FREDERICK,MD 21702

来源：

JOURNAL OF NATURAL PRODUCTS-LLOYDIA | 1995年 / 58卷 / 04期

关键词：

D O I：

10.1021/np50118a020

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Cytocoxicity-directed fractionation of an organic extract of the tunicaee Lissoclinum patella afforded a new cyclic octapeptide, patellamide F [1]. The structure and absolute stereochemistry of 1 were established by a combination of spectroscopic and chemical methods. Three known cyclic peptides, patellamide B [2], ulithiacyclamide, and lissoclinamide 3, were also isolated and identified.

引用

页码：594 / 597

页数：4

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