A ROUTE TO DIPEPTIDES CONTAINING BETA-AMINO-ALPHA-HYDROXY ACID FRAGMENTS BY COUPLING OF N-BOC-BETA-LACTAMS WITH ALPHA-AMINO ESTERS - APPLICATION TO THE SYNTHESIS OF (-)-BESTATIN

被引：47

作者：

PALOMO, C

AIZPURUA, JM

CUEVAS, C

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1994年 / 17期

关键词：

D O I：

10.1039/c39940001957

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

alpha-Amino esters are smoothly acylated by N-Boc-3-alkoxy-4-alkyl-beta-lactams in DMF under the influence of sodium azide, giving a novel dipeptide coupling reaction.

引用

页码：1957 / 1958

页数：2

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