INACTIVATION OF STREPTOMYCES-HYDROGENANS 20-BETA-HYDROXYSTEROID DEHYDROGENASE BY AN ENZYME-GENERATED ETHOXYACETYLENIC KETONE IN THE PRESENCE OF A THIOL SCAVENGER

被引：9

作者：

COVEY, DF

MCMULLAN, PC

WEAVER, AJ

CHIEN, WW

机构：

来源：

BIOCHEMISTRY | 1986年 / 25卷 / 23期

关键词：

D O I：

10.1021/bi00371a007

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

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页码：7288 / 7294

页数：7

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共 16 条

[1] AUCHUS RJ, 1986, BIOCHEMISTRY
[2] 4-ETHENYLIDENE STEROIDS AS MECHANISM-BASED INACTIVATORS OF 3-BETA-HYDROXYSTEROID DEHYDROGENASES
BALASUBRAMANIAN, V
MCDERMOTT, IR
ROBINSON, CH
[J]. STEROIDS, 1982, 40 (01) : 109 - 119
[3] IRREVERSIBLE INACTIVATION OF MAMMALIAN DELTA-5-3-BETA-HYDROXYSTEROID DEHYDROGENASES BY 5,10-SECOSTEROIDS - ENZYMATIC OXIDATION OF ALLENIC ALCOHOLS TO THE CORRESPONDING ALLENIC KETONES
BALASUBRAMANIAN, V
ROBINSON, CH
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1981, 101 (02) : 495 - 501
[4] REACTION MECHANISM AND STEREOSPECIFICITY OF 20 BETA-HYDROXYSTEROID DEHYDROGENASE
BETZ, G
WARREN, JC
[J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1968, 128 (03) : 745 - &
[5] REACTION MECHANISM OF 20BETA-HYDROXYSTEROID DEHYDROGENASE DETERMINED BY EQUILIBRIUM RATE EXCHANGE
BETZ, G
TAYLOR, P
[J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1970, 137 (01) : 109 - &
[6] THE SYNTHESIS OF 20-BETA,21-DIHYDROXY-4-PREGNEN-3-ONE AND 3,5-PREGNADIENE-20-BETA,21-DIOL
CASPI, E
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1956, 21 (07) : 729 - 732
[7] CARDENOLIDE ANALOGS .7. SYNTHESIS AND BIOLOGICAL-ACTIVITY OF SOME NEW STEROIDAL GUANYLHYDRAZONES
GELBART, A
THOMAS, R
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1978, 21 (03) : 284 - 288
[8] SOME EFFECTS OF RING-A STRUCTURE ON INTERACTION OF 3-OXO-STEROIDS OF ANDROSTANE SERIES WITH CORTISONE REDUCTASE
GIBB, W
JEFFERY, J
[J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1972, 25 (01): : 136 - &
[9] KITZ R, 1962, J BIOL CHEM, V237, P3245
[10] The determination of enzyme dissociation constants
Lineweaver, H
Burk, D
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1934, 56 : 658 - 666