VASOPRESSIN AND THE KINDLING OF SEIZURES

被引:12
作者
CORCORAN, ME [1 ]
CAIN, DP [1 ]
FINLAY, JM [1 ]
GILLIS, BJ [1 ]
机构
[1] UNIV WESTERN ONTARIO, DEPT PSYCHOL, LONDON N6A 5C2, ONTARIO, CANADA
关键词
D O I
10.1016/0024-3205(84)90660-X
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
A previous report that 2 intracerebroventricular injections of arginine-vasopressin (AVP) can kindle convulsive seizures [was investigated by injecting] AVP up to 14 times [in rats]. Although behavioral and electrographic effects were observed, seizures failed to develop with any reliability. These results call into question the phenomenon of AVP kindling. [Implications with respect to a possible role of AVP in fever associated seizures in children are presented.].
引用
收藏
页码:947 / 952
页数:6
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