PRESSURE-TUNING INFRARED AND SOLUTION RAMAN-SPECTROSCOPIC STUDIES OF 17-BETA-ESTRADIOL AND SEVERAL A-RING AND 17-ALPHA-ETHYNYLESTRADIOL DERIVATIVES

被引：11

作者：

BARNETT, SM

BUTLER, IS

TOP, S

JAOUEN, G

机构：

[1] MCGILL UNIV, DEPT CHEM, MONTREAL, PQ H3A 2K6, CANADA

[2] ECOLE NATL SUPER CHIM, F-75231 PARIS 05, FRANCE

来源：

VIBRATIONAL SPECTROSCOPY | 1995年 / 8卷 / 02期

基金：

加拿大自然科学与工程研究理事会;

关键词：

INFRARED SPECTROMETRY; RAMAN SPECTROMETRY; STEROIDS; PRESSURE TUNING; ORGANOMETALLICS;

D O I：

10.1016/0924-2031(94)00028-F

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The vibrational spectrum of the hormonal steriod (17)beta-estradiol has been assigned with the aid of pressure-tuning infrared (IR) and solution Raman spectroscopy. In addition, a pressure-tuning IR study of 17 alpha-ethynylestradiol suggests that the 17 alpha-ethynyl hydrogen is hydrogen bonded in the solid state. Related work on a series of organometallic estradiol derivatives indicates that the effect of substitution chiefly affects the pressure sensitivities of vibrational modes located near the point of substitution. For the alpha- and beta-[Cr(CO)(3)]-17 beta-estradiol diastereomers, several vibrational spectroscopic differences were noted and the alpha-[Cr(CO)(3)] fragment apparently has a steric effect on the extent of hydrogen bonding.

引用

页码：263 / 277

页数：15

共 101 条

[1] VIBRATIONAL SPECTROSCOPY AT HIGH-PRESSURES .59. AN INFRARED AND RAMAN-STUDY OF LITHIUM HYDROXIDE MONOHYDRATE - HYDROGEN-BOND FORMATION AT HIGH-PRESSURES [J].