INVITRO SUSCEPTIBILITY PATTERNS OF 121 FLAVOBACTERIUM STRAINS AGAINST 39 ANTIMICROBIAL AGENTS

被引:5
作者
MOULIN, V
FRENEY, J
HANSEN, W
PHILIPPON, A
机构
[1] Hôpital Saint-Louis, Service de Bactériologie-Virologie, F-75010 Paris
[2] Hôpital Ed. Herriot, Laboratoire de Microbiologie, Lyon
[3] Hôpital Universitaire Brugmann, Bruxelles
来源
MEDECINE ET MALADIES INFECTIEUSES | 1992年 / 22卷 / 11期
关键词
FLAVOBACTERIUM; F-MENINGOSEPTICUM; SUSCEPTIBILITY PATTERNS TO ANTIMICROBIAL AGENTS; INHIBITORS OF BETA-LACTAMASE;
D O I
10.1016/S0399-077X(05)80627-4
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
In vitro susceptibility of 121 strains of Flavobacterium species including F. meningosepticum, Flavobacterium IIb, F. breve, F. odoratum and Sphingobacterium sp. to 39 antimicrobial agents was performed by the agar diffusion method. 112 strains were multiresistant but susceptible to ureidopenicillins, rifampin and minocycline. Susceptibility patterns to 14 beta-lactams combined or not to clavulanic acid were clearly individualized between F. meningosepticum, F. multivorum or F. spiritivorum, F. odoratum, Flavobacterium IIb, F. breve. A synergy between amoxicillin or ticarcillin in combination with clavulanic acid was observed for all strains, except for those belonging to F. odoratum. A curious synergy was obtained between clavulanic acid and cephalosporins e.g. ceftazidime, cefotaxime for all strains of F. meningosepticum. A multivariate analysis of susceptibility results by the principal component analysis (PCA) and the graphic approach (MacSpin) showed such differentiation contributive for a fast and useful bacterial identification.
引用
收藏
页码:902 / 908
页数:7
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