EFFICACY OF CHLORHEXIDINE AND NYSTATIN RINSES IN PREVENTION OF ORAL COMPLICATIONS IN LEUKEMIA AND BONE-MARROW TRANSPLANTATION

被引：122

作者：

EPSTEIN, JB

VICKARS, L

SPINELLI, J

REECE, D

机构：

[1] UNIV BRITISH COLUMBIA,FAC MED,VANCOUVER V6T 1W5,BC,CANADA

[2] VANCOUVER GEN HOSP,DIV ORAL MED & CLIN DENT,VANCOUVER V5Z 1M9,BC,CANADA

[3] UNIV WASHINGTON,DEPT ORAL MED,SEATTLE,WA 98195

[4] ST PAULS HOSP,CLIN HEMATOL,VANCOUVER V6Z 1Y6,BC,CANADA

[5] BRITISH COLUMBIA CANC AGCY,DEPT EPIDEMIOL BIOMETRY & OCCUPAT ONCOL,VANCOUVER,BC,CANADA

[6] VANCOUVER GEN HOSP,LEUKEMIA BONE MARROW TRANSPLANT PROGRAM,VANCOUVER V5Z 1M9,BC,CANADA

来源：

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS | 1992年 / 73卷 / 06期

关键词：

D O I：

10.1016/0030-4220(92)90009-F

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

The goal of reducing oral complications during chemotherapy and bone marrow transplantation has received attention at several centers. The current randomized study of 86 adults with leukemia treated with chemotherapy or bone marrow transplantation assessed the potential role of chlorhexidine, nystatin, and saline solution rinses to reduce the findings of oral mucositis, gingivitis, and oral infection. The results of this study did not show a reduction in mucositis with the use of these rinses. However, potential bacterial and fungal pathogens were identified less frequently in the patients using chlorhexidine rinse.

引用

页码：682 / 689

页数：8

共 73 条

[1] CLOTRIMAZOLE TREATMENT FOR PREVENTION OF ORAL CANDIDIASIS IN PATIENTS WITH ACUTE-LEUKEMIA UNDERGOING CHEMOTHERAPY [J].

AVILES, A .

AMERICAN JOURNAL OF MEDICINE, 1987, 82 (04) :867-867

[2] EVALUATION OF NYSTATIN IN PREVENTION AND ELIMINATION OF OROPHARYNGEAL CANDIDA IN IMMUNOSUPPRESSED PATIENTS [J].

BARRETT, AP .

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS, 1984, 58 (02) :148-151

[3] A LONG-TERM PROSPECTIVE CLINICAL-STUDY OF ORAL COMPLICATIONS DURING CONVENTIONAL CHEMOTHERAPY FOR ACUTE-LEUKEMIA [J].

BARRETT, AP .

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS, 1987, 63 (03) :313-316

[4]

BENDER JF, 1979, EUR J CANCER, V15, P35

[5] ORAL INFECTIONS AND SEPTICEMIA IN IMMUNOCOMPROMISED PATIENTS WITH HEMATOLOGIC MALIGNANCIES [J].

BERGMANN, OJ .

JOURNAL OF CLINICAL MICROBIOLOGY, 1988, 26 (10) :2105-2109

[6]

BERKOWITZ RJ, 1983, AM J PEDIAT HEMATOL, V5, P53

[7]

BERKOWITZ RJ, 1985, AM J PEDIAT HEMATOL, V7, P82

[8]

BODEY GP, 1978, CANCER, V41, P1610, DOI 10.1002/1097-0142(197804)41:4<1610::AID-CNCR2820410452>3.0.CO

[9]

2-B

[10] TREATMENT OF ORAL CANDIDIASIS IN DEBILITATED PATIENTS WITH MICONAZOLE - NEW POTENT ANTIFUNGAL DRUG [J].

BRINCKER, H .

SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES, 1976, 8 (02) :117-120

← 1 2 3 4 5 6 7 8 →