THE OXIDATION OF ASCORBIC-ACID AT CARBON PASTE ELECTRODES - MODIFIED RESPONSE FOLLOWING CONTACT WITH SURFACTANT, LIPID AND BRAIN-TISSUE

被引：57

作者：

ORMONDE, DE ^{[1
]}

ONEILL, RD ^{[1
]}

机构：

[1] NATL UNIV IRELAND UNIV COLL DUBLIN,DEPT CHEM,DUBLIN 4,IRELAND

来源：

JOURNAL OF ELECTROANALYTICAL CHEMISTRY | 1990年 / 279卷 / 1-2期

关键词：

D O I：

10.1016/0022-0728(90)85170-A

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The electrochemical characteristics of ascorbic acid and ferrocyanide were investigated at untreated, surfactant (Triton-X) treated and lipid (phosphatidylethanolamine) treated carbon paste electrodes (CPEs), at carbon powder electrodes, and at CPEs following contact with brain tissue. The results indicate that, following contact with brain tissue, pasting oil is removed (apparently by lipids present in the tissue) from the active surface of the electrode. Resistance and capacitance studies support this interpretation. Electron transfer at the resulting powder-type surface is faster than at the original CPE, leading to a shift in the oxidation wave for ascorbic acid to lower potentials. Adsorption of substrate on the electrode is evident following, but not before, the treatments. Implications for the development of chemically modified CPEs for use in vivo are discussed. © 1990.

引用

页码：109 / 121

页数：13

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