PROPHYLACTIC ENDOVASCULAR RADIOTHERAPY TO PREVENT INTIMAL HYPERPLASIA AFTER STENT IMPLANTATION IN FEMOROPOPLITEAL ARTERIES

被引:137
作者
LIERMANN, D
BOTTCHER, HD
KOLLATH, J
SCHOPOHL, B
STRASSMANN, G
STRECKER, EP
BREDDIN, KH
机构
关键词
ATHEROSCLEROSIS; STENT; INTIMAL HYPERPLASIA; PROPHYLAXIS; CONTRAST RADIATION; AFTERLOADING TECHNIQUE;
D O I
10.1007/BF01102065
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose: Recurrent stenosis or occlusion by intimal hyperplasia occurs in up to 40% of patients with tantalum stent implantations in femoropopliteal arteries and greatly restricts their usefulness. We evaluated the effect of prophylactic endovascular radiotherapy on stenosed/occluded stents. Methods: We investigated prophylactic endovascular radiotherapy with a surface dose of 12 Gy using an iridium 192 source as a means to reduce or eliminate recurrent stenosis in 4 patients with stenosed/occluded stents, 6-8 months after the original implantation. Confirmatory diagnostic atherectomy, PTA or laser recanalization and endovascular radiotherapy were performed. Results: None of the four has developed recurrent obstruction within 23 to 30 months after this treatment, which up to now shows no short-term or long-term complications. Conclusion: We conclude that this limited experience is promising enough to warrant further study.
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页码:12 / 16
页数:5
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