MICROBIAL ALKENE EPOXIDATION - MERITS AND LIMITATIONS

被引：12

作者：

ONUMONU, AN

COLOCOUSSI, A

MATTHEWS, C

WOODLAND, MP

LEAK, DJ

机构：

[1] Centre for Biotechnology, Department of Biochemistry, Imperial College of Science, Technology and Medicine, London

来源：

BIOCATALYSIS | 1994年 / 10卷 / 1-4期

关键词：

EPOXIDE; ALKANE MONOOXYGENASE; ALKENE MONOOXYGENASE; MICROBIAL OXIDATION;

D O I：

10.3109/10242429409065230

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The direct epoxidation of olefins using monooxygenases offers the realistic prospect of stoichiometric conversion of a pro-chiral substrate into an enantiomerically pure product. A number of microbial systems are available in which the mechanism of oxygen activation, and consequently the oxygen reactivity, differs. This paper discusses some of the merits and potential problems associated with these different systems.

引用

页码：211 / 218

页数：8

共 23 条

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