SUPPRESSING EFFECT OF LACTOBACILLUS-CASEI ADMINISTRATION ON THE URINARY MUTAGENICITY ARISING FROM INGESTION OF FRIED GROUND-BEEF IN THE HUMAN

被引：79

作者：

HAYATSU, H

HAYATSU, T

机构：

[1] Faculty of Pharmaceutical Sciences, Okayama University, Tsushima, Okayama

来源：

CANCER LETTERS | 1993年 / 73卷 / 2-3期

关键词：

URINARY MUTAGENICITY; COOKED BEEF; LACTOBACILLUS-CASEI;

D O I：

10.1016/0304-3835(93)90261-7

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

It is known that the ingestion of cooked meat which contains carcinogenic heterocyclic amines causes increase in urinary mutagenicity in humans. Using 6 healthy non-smokers, we examined the effect of 3-week oral administration of Lactobacillus casei (bacilli commonly present in yoghurt), on the urinary mutagenicity derived from ingestion of fried ground beef. Comparison of the urinary mutagenicity found before and after the L. casei treatment showed that the treatment resulted in a decrease (6-67%, average 47.5%) of the mutagenicity. This suppressing effect is possibly related to the changes in the intestinal microflora population.

引用

页码：173 / 179

页数：7

共 22 条

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