A DOUBLE-BLIND-STUDY OF THE EFFICACY OF METRONIDAZOLE GEL IN THE TREATMENT OF MALODOROUS FUNGATING TUMORS

被引：33

作者：

BOWER, M

STEIN, R

EVANS, TRJ

HEDLEY, A

PERT, P

COOMBES, RC

机构：

[1] CHARING CROSS HOSP,DEPT MED ONCOL,FULHAM PALACE RD,LONDON W6 8RF,ENGLAND

[2] FARMITALIA CARLO ERBA LTD,ALBANS,HERTS,ENGLAND

[3] ST GEORGE HOSP,CLIN ONCOL UNIT,LONDON SW17 0QT,ENGLAND

来源：

EUROPEAN JOURNAL OF CANCER | 1992年 / 28A卷 / 4-5期

关键词：

D O I：

10.1016/0959-8049(92)90142-O

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A double-blind placebo-controlled trial was undertaken to assess the value of topical metronidazole gel preparation in the palliation of the offensive odour of fungating tumours. This 5 day trial was followed by a 6 day period during which all patients received the active gel. Subjective odour assessments were performed by both patients and medical staff. 11 patients were entered and the randomisation was then halted because of an obvious overall benefit over the whole 11 days. There was a non-significant trend in favour of the active treatment during the initial double-blind placebo-controlled phase of the trial, and no side-effects were observed.

引用

页码：888 / 889

页数：2