COLOCALIZATION OF PROLACTIN-LIKE AND DYNORPHIN-LIKE SUBSTANCES IN A NEURONAL POPULATION OF THE RAT LATERAL HYPOTHALAMUS

被引：37

作者：

GRIFFOND, B ^{[1
]}

DERAY, A ^{[1
]}

FELLMANN, D ^{[1
]}

CIOFI, P ^{[1
]}

CROIX, D ^{[1
]}

BUGNON, C ^{[1
]}

机构：

[1] INSERM,U156,F-59045 LILLE,FRANCE

来源：

NEUROSCIENCE LETTERS | 1993年 / 156卷 / 1-2期

关键词：

RAT BRAIN; LATERAL HYPOTHALAMUS; IMMUNOCYTOCHEMISTRY; PRL-LIKE SUBSTANCE; DYN B-LIKE SUBSTANCE;

D O I：

10.1016/0304-3940(93)90447-S

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Using an antiserum (AS) raised against dynorphin B (DYN B), we revealed immunoreactive neurons in different nuclei of the rat hypothalamus as well as a population of neurons scattered in the lateral areas of the posterior hypothalamus. This population corresponds to that previously shown to be specifically recognized by an ovine prolactin (PRL) AS. Our results suggest that in these neurons, DYN B and PRL AS reacted with different epitopes and that these epitopes could be carried by distinct unidentified peptides.

引用

收藏

页码：91 / 95

页数：5

相关论文

共 29 条

[1] AXONS CONTAINING A PROLACTIN-LIKE PEPTIDE PROJECT INTO THE PERIVASCULAR LAYER OF THE MEDIAN-EMINENCE - AN IMMUNOCYTOCHEMICAL LIGHT AND ELECTRON-MICROSCOPE STUDY IN ADULT AND INFANT RATS [J].

ALONSO, G ;

SIAUD, P ;

FAIVRESARRAILH, C ;

GROUSELLE, D ;

BARBANEL, G ;

ASSENMACHER, I .

NEUROENDOCRINOLOGY, 1988, 48 (01) :39-44

[2] THE MELANIN-CONCENTRATING HORMONE SYSTEM OF THE RAT-BRAIN - AN IMMUNIZATION AND HYBRIDIZATION HISTOCHEMICAL CHARACTERIZATION [J].

BITTENCOURT, JC ;

PRESSE, F ;

ARIAS, C ;

PETO, C ;

VAUGHAN, J ;

NAHON, JL ;

VALE, W ;

SAWCHENKO, PE .

JOURNAL OF COMPARATIVE NEUROLOGY, 1992, 319 (02) :218-245

[3] ESTRADIOL INCREASES PROLACTIN SYNTHESIS AND PROLACTIN MESSENGER-RIBONUCLEIC-ACID IN SELECTED BRAIN-REGIONS IN THE HYPOPHYSECTOMIZED FEMALE RAT [J].

DEVITO, WJ ;

AVAKIAN, C ;

STONE, S ;

ACE, CI .

ENDOCRINOLOGY, 1992, 131 (05) :2154-2160

[4] COMPARISON OF BRAIN AND PITUITARY IMMUNOREACTIVE PROLACTIN BY PEPTIDE-MAPPING AND LECTIN AFFINITY-CHROMATOGRAPHY [J].

DEVITO, WJ .

ENDOCRINOLOGY, 1989, 125 (05) :2439-2444

[5] HYPOTHALAMIC PROLACTIN - CHARACTERIZATION BY RADIOIMMUNOASSAY AND BIOASSAY AND RESPONSE TO HYPOPHYSECTOMY AND RESTRAINT STRESS [J].

EMANUELE, NV ;

METCALFE, L ;

WALLOCK, L ;

TENTLER, J ;

HAGEN, TC ;

BEER, CT ;

MARTINSON, D ;

GOUT, PW ;

KIRSTEINS, L ;

LAWRENCE, AM .

NEUROENDOCRINOLOGY, 1986, 44 (02) :217-221

[6]

Fallon J.H., 1990, HDB CHEM NEUROANATOM, V9, P1

[7] DISTRIBUTION OF DYNORPHIN AND ENKEPHALIN PEPTIDES IN THE RAT-BRAIN [J].

FALLON, JH ;

LESLIE, FM .

JOURNAL OF COMPARATIVE NEUROLOGY, 1986, 249 (03) :293-336

[8] UNRELATED PEPTIDE IMMUNOREACTIVITIES COEXIST IN NEURONS OF THE RAT LATERAL DORSAL HYPOTHALAMUS - HUMAN GROWTH HORMONE-RELEASING FACTOR1-37-, SALMON MELANIN-CONCENTRATING HORMONE-LIKE AND ALPHA-MELANOTROPIN-LIKE SUBSTANCES [J].

FELLMANN, D ;

BUGNON, C ;

RISOLD, PY .

NEUROSCIENCE LETTERS, 1987, 74 (03) :275-280

[9]

FELLMANN D, IN PRESS NEUROPEPTID

[10] PROLACTIN-LIKE IMMUNOREACTIVITY - LOCALIZATION IN NERVE-TERMINALS OF RAT HYPOTHALAMUS [J].

FUXE, K ;

HOKFELT, T ;

ENEROTH, P ;

GUSTAFSSON, JA ;

SKETT, P .

SCIENCE, 1977, 196 (4292) :899-900