RENAL MICROANGIOPATHY IN THE PRIMARY ANTIPHOSPHOLIPID SYNDROME - A CASE-REPORT WITH LITERATURE-REVIEW

被引：22

作者：

DOMRONGKITCHAIPORN, S

CAMERON, EC

JETHA, N

KASSEN, BO

SUTTON, RAL

机构：

[1] VANCOUVER GEN HOSP,DEPT MED,DIV NEPHROL,VANCOUVER,BC,CANADA

[2] UNIV BRITISH COLUMBIA HOSP,DEPT INTERNAL MED,VANCOUVER,BC,CANADA

[3] UNIV BRITISH COLUMBIA HOSP,DEPT ANAT PATHOL,VANCOUVER,BC,CANADA

来源：

NEPHRON | 1994年 / 68卷 / 01期

关键词：

ANTIPHOSPHOLIPID SYNDROME; RENAL MICROANGIOPATHY; ACUTE RENAL FAILURE;

D O I：

10.1159/000188231

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

We report the case of a 52-year-old male patient with recurrent thrombosis from 'primary antiphospholipid syndrome' who developed renal microangiopathy. Despite anticoagulant therapy with coumadin, serum creatinine progressively increased from 398 to 592 mu mol/l and platelets decreased to 43,000. The patient responded to high-dose methylprednisolone and aspirin and the renal function improved. A review of the literature disclosed 4 other cases of association between primary antiphospholipid syndrome and renal microangiopathy. The clinical characteristics of these cases are discussed.

引用

页码：128 / 132

页数：5

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